FALL FACULTY ASSEMBLY MEETING November 14, 2017 Frontiers: University of Kansas Clinical and Translational Science Institute KU CTSI OUR THREE SIMPLE GOALS: 1. Support researchers 2. Train researchers 3. Grow the research enterprise THE WIDER CONTEXT KUMC investigators submitted $547m in new grants KUMC was awarded $105m KUMC expended $120m New and Renewed Infrastructure Grants: Alzheimers Disease Center Cancer Center KIDDRC (KS Intellectual and Developmental Disabilities Research Center)

COBRE (Center of Biomedical Research Excellence; 2 awards) Frontiers FRONTIERS: University of Kansas Clinical and Translational Institute (KU CTSI) KUMC was awarded $25m over 5 years Year 1 runs September 7, 2017 June 30, 2018 Principal Investigator: Richard Barohn Associate Directors: Kim Kimminau & William Brooks Administrative Director: Jen Baker Assistant Administrative Director: Robin Liston FRONTIERS ASPIRATIONS BETTER RESOURCES FOR INVESTIGATORS EXPANDED NAVIGATORS PROGRAM Navigators assist investigators with ALL aspects of conducting human translational research PROMOTE LINKAGES THROUGH TEAM SCIENCE Collaborations that cross disciplines and leverage the regions and states institutions EDUCATION

Educating the current and next generation of clinical and translational researchers NIH Awards KUMC was awarded $105m in new awards More than $30m than last year New awards for FY 16 = $73m Have over 700 clinical trials and brought in $15m in revenue - Up $900K NIH Awards by category for FY17 RO1 RO1 Supplements RO3 R56 R21 P30 P30 Supplements KO1 K23 F31 F32 R13

U Awards S Equipment Grant 20 5 1 1 8 2 1 2 1 1 2 2 2 1 2017 Frontiers Stimulus Awardees

Ongoing funded projects $10K 20K each NIH Prior Approval Spend by 6/30/18 SOM - Crystal Lumpkins, Tribal and Urban Health Communication Investigating how American Indian Leaders and Elders throughout the Midwest Perceive Themselves as Health Promoters SON - Janet Pierce, Reducing Symptom Burden in Patients with Heart Failure with Preserved Ejection Fraction Using Ubiquinol and/or D-Ribose SHP - Neena Sharma, Opioid and Rehabilitation Following Lumbar Spine Surgery SHP - Catherine Siengsukon, Cognitive Behavioral Therapy for Insomnia to Address Insomnia Symptoms in People with Multiple Sclerosis KU Wichita - Matt Macaluso, Augmentation versus Switch: Comparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders with Treatment Resistant Depression CMH - Melissa Miller, Enhanced Intervention to Improve Adolescent Outcomes: A Clinical Trial CMH - Jennifer Shuster, Evaluation of Neuraminidase Antibodies in Pediatric Stem Cell Transplant Patients Receiving High versus Standard Dose Influenza Vaccine St. Lukes - John Spertus, The Impact of i2b2 on Evaluation of the Primary Care Centered Lung Cancer Screening Protocol Using an Epic Application CMH/UMKC - Tamorah Lewis/Paula Nichols, Single Nucleotide Polymorphisms (SNPs) in Genes Responsible for Steroid Metabolism and Response in Preterm Infants with Bronchopulmonary Dysplasia Organization of



Waitman Informatics: McMahon Clinical Informatics: Wennberg Community & Collaboration Greiner Team Science: Murray Community/ISP: TBN Translational Endeavors Spertus / Smith Implementation: TBN Entrepreneurship: Nagel/Meyer Research Methods Mayo Caldwell/Blackwell

Statistics: Tremblay RKS: Hindle Hub Research Capacity Berkley-Patton/Maliski Clements/Burns Community/ISP: TBN PCI Navigator: Lahner Network Capacity Kluding / Blackwell IRB/Reliance: Griffith Recruitment/RTIU: Murray IAMI Weir / Leeder Schorno

KL2 Ellerbeck / Spertus Kerling TL1 Choi / Leeder Kerling FRONTIERS CORES INFORMATICS Waitman HERON Support regional access to resource Research in clinical workflow Conduct deep phenotyping

ADMINISTRATI ON Improve education, research quality and compliance Through secure data management, streamlining and effective tools for collaboration FRONTIERS CORES COMMUNITY AND COLLABORATION Greiner Kimminau/Brooks Berkley-Patton/ Maliski ADMINISTRATI ON Community and Special Population Support linkages to recruitment sites, community organization

partners, instruction in bootcamp methods, translation services Team Science Schedule and coordinate brainstorming sessions Collision Mixers Improve exposure and education regarding reaching vulnerable and underrepresented participants FRONTIERS CORES Implementation Science Entrepreneurship ADMINISTRATI ON TRANSLATIO NAL ENDEAVORS Spertus / Smith

Training Center Hub for training available through K & T programs, research methods/RKS, informatics, community, team science and IAMI Pilot Awards Stimulus Grants Trailblazer Awards Dr. Lauren Aaronson BERD Special Populations IAMI Entrepreneurship Consortium Pilot Awards FRONTIERS CORES Ensure optimal study design Encourage use of novel statistical methods Educate/train investigators and staff in biostatistics and regulatory requirements

ADMINISTRATI ON RESEARCH METHODS Mayo Caldwell Support for protocol, consent, IND/IDE, adverse event reporting, safety and regulatory management, compliance, IP Research and Discovery Grand Rounds Clinical Research Coordinator Bootcamp Research Personnel Networking GCP and RCR training FRONTIERS CORES ADMINISTRATIO N HUB RESEARCH CAPACITY Berkley-Patton /

Maliski Clements / Burns Engage special populations in translational research ISP Workgroup Close collaboration with Community and Recruitment experts Diversity Trailblazer Awards Foundation and support to conduct human subjects research CTSU FRONTIERS CORES ADMINISTRATI ON NETWORK

CAPACITY Kluding Blackwell Multi-site trial facilitation Start-up Single IRB Contracts and budgeting Project management support Speed trial completion with effective recruitment/retention resources and expertise Connect to NCATS Trial Innovation Network FRONTIERS CORES Product development Methods Lifespan focused ADMINISTRATI ON

INSTITUTE FOR ADVANCING MEDICAL INNOVATION Weir / Leeder Collaborate with local, regional and national partners to develop/demonstrate Drug development Diagnostic technologies Medical device technologies Mentorship FRONTIERS CORES CAREER DEVELOPMEN T CORE -KL2 Ellerbeck / Spertus

Support junior scientists Mentors Tools Experiences MSCR degree ADMINISTRATI ON Encourage recruitment of diverse pool Evaluate to drive continuous improvement FRONTIERS CORES Foster career development Interdisciplinary teams Mentors Training TRAINING CORE -TL1 Choi / Leeder

ADMINISTRATI ON Recruit highly promising and diverse pool of pre-doctoral and post-doctoral trainees Evaluate effectiveness FRONTIERS CORES TRAINING CORE TL1 CAREER DEVELOPMEN T CORE KL2 INFORMATICS COMMUNITY


Questions? Contact the Frontiers Office for assistance 913-588-6290

Recently Viewed Presentations

  • INTERNET - WordPress.com

    INTERNET - WordPress.com

    Berbelanja melalui internet. 2002 Medial sosial internet Friendster didirikan oleh Jonathan Abrams and Peter Chin 2003 Medial sosial internet My Space didirikan oleh Tom Anderson 2004 Medial sosial internet Facebook didirikan oleh Mark Zuckerberg. Hingga kini Facebook telah digunakan oleh...
  • Project Overview Geospatial Technician Education Through Virginias Community

    Project Overview Geospatial Technician Education Through Virginias Community

    Create and sustain a GST web portal to serve as a repository for GST pathway models, curriculum, professional development materials, and other resources. We will provide you with a guided tour of the VCCS Geospatial Portal tomorrow!
  • EVENT, DATE MNS-Up Power distribution and UPS in

    EVENT, DATE MNS-Up Power distribution and UPS in

    Data centers need compact, configurable, switchgear and UPS that are easy to buy, install and maintain. Scale - fewer, larger facilities. Diversity of supply - multiple power sources. Intelligence - smart components that communicate and self-supervise. Failing small - failures...
  • Anne Houtman  Megan Scudellari  Cindy Malone Biology  Now

    Anne Houtman Megan Scudellari Cindy Malone Biology Now

    Figure 9.11. A point mutation in the hemoglobin gene leads to sickle-cell disease. In people with the genetic disorder sickle-cell disease, a single base in the gene that makes hemoglobin, an important protein involved in oxygen transport in red blood...
  • CPSC 411 Design and Analysis of Algorithms

    CPSC 411 Design and Analysis of Algorithms

    Show claim is true for iteration i+1. During iteration i, p i is under consideration, and some points might be popped off S in the while loop due to nonleft-turn check. Let p j be top of S after all...
  • Old Hungarian: Halfway between Ugric and Modern Hungarian

    Old Hungarian: Halfway between Ugric and Modern Hungarian

    OH: definitenessderivedfrommeaning, O-Vagreement, position, etc. (25) vylag. nem vallót oly czudasemberek-eth. worldnot had suchwonderfulpeople-ACC ' the. world. didnothavesuchwonderfulpeople' (26) anyath
  • Education - letort.carlisleschools.org

    Education - letort.carlisleschools.org

    Planning. Difficulty setting and achieving goals. Difficulty breaking tasks into manageable . chunks . This is the issue for long term projects.. Or even something as simply as students have choices during the time they are not in small or...
  • Unit: 3 Chapter 7: Branding and Licensing

    Unit: 3 Chapter 7: Branding and Licensing

    Reflect an Image. Should say something about the product. Wheaties cereal has used athletes on its packaging and is known as The Breakfast of Champions. The positive association with the sports industry helps to create a distinctive image of Wheaties...