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Master of Science in Biostatistics Information Session Emilia Bagiella, PhD & Emma K. T. Benn, DrPH Program Co-Directors Web: www.icahn.mssm.edu/MSbiostat Email: [email protected] Overview 1. About ISMMS 2. The Center for Biostatistics at ISMMS 3. What is Biostatistics? 4. Master of Science in Biostatistics Theory & Methods Program Overview

Program Eligibility Curriculum Admissions Tuition & Financial Aid 5. Careers and Opportunities in Biostatistics WELCOME TO THE ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI! About ISMMS 1. Chartered in 1963 2. Mission is to rigorously train the next generation of scientists and health professionals. 3. Almost 1200 graduate and medical students enrolled in the 2014/2015 year 4. Leader in medical and scientific training, biomedical research and patient care. 5. Committed to intellectual exchange, multidisciplinary teamwork and innovation that can lead to discoveries and advances to improve the human condition.

Research at ISMMS The Center for Biostatistics at ISMMS Established in 2011 16 faculty members 10 MS statisticians Promote successful clinical and translational research at Mount Sinai

Educate medical students, graduate students, postdoctoral fellows, and other research staff The Center for Biostatistics at ISMMS 1. Educational Programs MPH Biostatistics track MS in Biostatistics Theory and Methods Track Clinical Applications Track (For Clinical Professionals) Biostatistics Summer Program for Clinical Research The Applied Statistics in Biological Systems (ASIBS) Short Course Support to the Clinical Research Program Examples of research our MS Biostatisticians have contributed to:

Surgical ablation of atrial fibrillation during mitral-valve surgery. Gillinov AM, Gelijns AC, Parides MK, DeRose JJ Jr, Moskowitz AJ, Voisine P, Ailawadi G, Bouchard D, Smith PK, Mack MJ, Acker MA, Mullen JC, Rose EA, Chang HL, Puskas JD, Couderc JP, Gardner TJ, Varghese R, Horvath KA, Bolling SF, Michler RE, Geller NL, Ascheim DD, Miller MA, Bagiella E, Moquete EG, Williams P, Taddei-Peters WC, O'Gara PT, Blackstone EH, Argenziano M; CTSN Investigators. N Engl J Med. 2015 Apr 9;372(15):1399-409 Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial. Mohr JP, Parides MK, Stapf C, Moquete E, Moy CS, Overbey JR, Al-Shahi Salman R, Vicaut E, Young WL, Houdart E, Cordonnier C, Stefani MA, Hartmann A, von Kummer R, Biondi A, Berkefeld J, Klijn CJ, Harkness K, Libman R, Barreau X, Moskowitz AJ; international ARUBA investigators. Lancet. 2014 Feb 15;383(9917):614-21. Costs associated with health care-associated infections in cardiac surgery. Greco G, Shi W, Michler RE, Meltzer DO, Ailawadi G, Hohmann SF, Thourani VH, Argenziano M, Alexander JH, Sankovic K, Gupta L, Blackstone EH, Acker MA, Russo MJ, Lee A, Burks SG, Gelijns AC, Bagiella E, Moskowitz AJ, Gardner TJ. J Am Coll Cardiol. 2015 Jan 6;65(1):15-23.

Effect of peer education on stroke prevention: the prevent recurrence of all inner-city strokes through education randomized controlled trial. Kronish IM, Goldfinger JZ, Negron R, Fei K, Tuhrim S, Arniella G, Horowitz CR. Stroke. 2014 Nov;45(11):3330-6. What is Biostatistics? http://www.worldofstatistics.org/2013/02/11/biostatistics-unveiled/ What is Biostatistics? Biostatistics is a branch of statistics that allows for the analysis and interpretation of scientific data generated in the clinical, public health, biomedical and translational sciences. "By a small sample, we may judge of the whole piece." Miguel de Cervantes (from Don Quixote)

What is Biostatistics? Business Economics, Engineering, Marketing, Computer Science Health & Medicine Genetics, Clinical Trials, Epidemiology, Pharmacology Physical Sciences Astronomy, Chemistry, Physics Areas where STATISTICS are used

Environment Agriculture, Ecology, Forestry, Animal Populations Government Census, DOH, NCHS, CDC, FDA, NIH Adapted Figure from the American Statistical Association Master of Science in Biostatistics Program Overview 1. Sponsored by Center for Biostatistics & Department of Population Health Science and Policy at ISMMS 2. Designed to prepare individuals for: Career as data analysts and applied statisticians in the biomedical sciences

PhD/DrPH in Biostatistics or Epidemiology or Bioinformatics 3. Distinctive, accelerated design One year, full-time program Comprehensive didactic training for conducting high-quality clinical and translational research Curriculum emphasizes strong quantitative training to address complex challenges 4. Student-centered Small cohort size (5 10 students) Excellent mentorship and individualized attention 5. Uniquely positioned

The Graduate School of Biomedical Sciences Science That Changes Medicine The Graduate School is uniquely positioned within a worldclass medical school and health system. We have broken down the barriers to collaboration, allowing students to connect science, biostatistics, medicine, education and health care delivery. Programs Across the Translational Health Continuum Basic Sciences PhD Multidisciplinary Training Areas PhD Program (Basic Sciences) MD/PhD Program MS in Biostatistics MS in Biomedical Sciences PhD in Clinical Research MS Clinical Research MS in Genetic Counseling MS in Health Care Delivery Leadership Masters in Public Health MSW/MPH

Summer Undergraduate Research Program Post Baccalaureate Research Education Program Clinical Research Education Program Advanced Certificate in Public Health Physician Scholars PhD Program Cancer Biology Developmental and Stem Cell Biology Design, Technology and Entrepreneurship Genetics and Genomic Sciences

Immunology Microbiology Neuroscience Systems Biology of Disease and Therapeutics Structural/Chemical Biology and Molecular Design Quick Facts Ranked 4th among U.S. medical schools for sponsored funding per investigator Over 225 Research Laboratories Master of Science in Biostatistics Program Eligibility 1. To be eligible for the MS in Biostatistics Program Theory & Methods Track, students must have:

At least two semesters of college-level calculus w/ grade of B or higher At least 1 college-level linear algebra course w/ grade of B or higher TOEFL for applicants from non-English speaking countries GRE (optional) 2. Prior exposure to statistics/biostatistics not required 3. Knowledge of mathematical/statistical programming language not required, but certainly helpful Master of Science in Biostatistics Curriculum 1. One year curriculum = 31 core credits + 3 elective credits FALL TERM Course Title Credits Introduction to Advanced Biostatistics Fundamentals of Epidemiology

Probability & Inference I Introduction to R Programming Capstone Clinical Trials Management (Elective) 3 3 3 1 1 3 SPRING I TERM Course Title Credits Theory of Linear and GLMs Analysis of Categorical Data Probability & Inference II

Applied Biostatistics in Clinical Trials Capstone 3 3 3 3 1 SPRING II TERM Course Title Credits Analysis of Longitudinal Data Survival Analysis Capstone Pharmacoeconomics (Elective) Race and Causal Inference (Elective) Required Credits

Minimum Elective Credits Total Credits 3 3 1 3 3 31 3 34 Master of Science in Biostatistics Curriculum 1. Capstone Objectives Engage students in important discourse surrounding data management and research ethics Fall Term

Challenge students to operationalize conceptual research questions into testable hypotheses and to determine the appropriate analytic methods to test their hypotheses Spring I Term Provide students with the opportunity to shadow Biostatistics faculty in the Center for Biostatistics consultation service Spring II Term Learn how to successfully collaborate with non-statisticians (primarily clinical faculty) at ISMMS Contribute appropriate study design-related and methodologic solutions to cutting edge research questions Conduct mentor-guided preliminary analyses Disseminate findings to an institution-wide audience at the annual MS in

Biostatistics Capstone Symposium Master of Science in Biostatistics Admissions 1. Theory & Methods Track Fall Application Deadline 1. Priority Application Deadline: January 15th 2. Final Application Deadline: February 15th 2. Online application: https://applygs.mssm.edu 3. Application components Online application Official Transcripts undergraduate and graduate (if applicable)

Mail to: ISMMS Office of Admissions One Gustave L. Levy Place Box 1002 New York, NY, 10029 Two Letters of Recommendation Background and demographics Personal statement (700 words) motivation for applying and post-graduation career objectives Current CV or resume Non-refundable application fee ($80)

Recommenders email LORs directly to [email protected] GRE (optional) and TOEFL (if international and non-English speaking) to School Code 2464 Master of Science in Biostatistics Tuition & Financial Aid 1. Application fee $80 2. Tuition is currently $41K 3. Student and Activity Fees are $150 4. Health Insurance Required 5. Financial Aid Available Master of Science in Biostatistics Tuition & Financial Aid 1. Eligible students submit the FAFSA. (US Citizen/eligible non-citizen)

2. Types of aid available -Stafford Loans -Federal Direct Graduate PLUS -Private Loans 3. We recommend applying for financial aid by August 1 st 4. School code is G07026 5. FAFSA Website https://fafsa.ed.gov/ Master of Science in Biostatistics Tuition & Financial Aid Stafford Loans Unsubsidized $26,000/year Repayment begins 6 months after graduation Direct Plus Loans Credit based and covers full out-of-pocket cost including living expenses Repayment begins immediately, but can be deferred while enrolled

Master of Science in Biostatistics Resources ISMMS: www.icahn.mssm.edu Center for Biostatistics: www.icahn.mssm.edu/centerforbiostatistics MS in Biostatistics Program Website: www.icahn.mssm.edu/MSbiostat MS in Biostatistics Program Email: [email protected]

MS in Biostatistics Program Co-Directors: Emilia Bagiella, PhD [email protected] Emma K. T. Benn, DrPH [email protected] MS in Biostatistics Administrative Educational Coordinator: Mary Sandre [email protected] Housing Resources: International House of New York: http://www.ihouse-nyc.org Hotel Alexander: http://www.hotelalexandernyc.com/student_housing.html Careers and Opportunities in Biostatistics Biostatisticians with advanced degrees can look forward to excellent career opportunities in government, industry, and academia. American Statistical Association

Career opportunities: Academic Medical Centers Pharmaceutical Industry Contract Research Organizations (CROs) US Food and Drug Administration Centers for Disease Control & Prevention State Departments of Health US Census Bureau National Institutes of Health Foundations

Careers and Opportunities in Biostatistics 1. Clinical Trials Design and Conduct 2. Public Health applications 3. Quality Control 4. Genetics and Genomics 5. Basic Sciences 6. Personalized Medicine 7. Big Data 8. Teaching Careers and Opportunities in Biostatistics 1. Job placement within 3-4 months from graduation 2. Median salary at first hire : $60K - $70K 3. Opportunities for growth 25

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