Optical Quality of the Synchrony IOL

Optical Quality of the Synchrony IOL

The Synchrony IOL is not currently FDA-approved 1 OPTICAL QUALITY OF DUAL-OPTIC ACCOMMODATING INTRAOCULAR LENS Andrea Galvis, MD 1 1,3 a Ivan Ossma, MD MPH MSc 1,2, a Sanjeev Kasthurirangan, PhD Fundacion Valle del Lili, Cali-Colombia

2 Universidad Industrial de Santander, Bucaramanga-Colombia 4, b 3 Universidad Autonoma de Bucaramanga, Bucaramanga-Colombia 4 Abbott Medical Optics Inc, Irvine, USA Financial Disclosure a b

Consultant Abbott Medical Optics Scientist at Abbott Medical Optics Inc. 2 Synchrony Design Anterior Optic 32 Diopters Posterior Divergent (negative) Optic Study Purpose

+ + Compare Optical Quality Pseudophakic Eyes + Monofocal IOL + Synchrony Dual Optic Accommodating IOL Parameters +

Objective iTrace aberrometry + + Custom Matlab Software to calculate MTF Subjective Contrast Sensitivity Testing + Optec 6500 3 Study Population

iTrace aberrometry Cycloplegia Monofocal IOL : 15 subjects (30 eyes) Synchrony IOL : 16 subjects (32 eyes)

3 mm zone Matlab Software to calculate MTF 4 5 iTrace - Matlab conversion 6 Results Objective Measurements 3 mm pupil Difference 0.01 um

7 Best-focus MTF 3 mm pupil Differences are less than 10% 8 Mesopic Contrast Sensitivity p=0.61 Wilcoxon Rank Sum Test 9 1 0

Discussion Dual Optic Design DOES NOT affect optical or retinal image quality of the eye Objective evidence (iTrace, MTF) Subjective evidence (CSF) Contrast sensitivity of Synchrony equivalent to that of is monofocal IOLs Discussion Effect of the slight spherical

aberration on Synchrony would only yield 0.42 D of increased depth of focus Calculations based on Rochas work * The improved near vision of Synchrony patients MOST LIKELY due to true accommodation * Rocha KM. Using Adaptive Optics Simultion to Explore the Effect of Higher Order Aberrations on Depth of Focus for the Correction of Presbyopia. Wavefront Congress 2008

1 1 Conclusion Quality of Vision of Synchrony IOL similar to standard monofocal IOLs Measured Subjectively Measured Objectively

Improved Near Vision with Synchrony Not related to increased depth of focus 1 2

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